Dealing With Alzheimer's

Have you or someone you know been diagnosed with Alzheimer’s. If yes you may be eligible to participate in the studies. apgresearch.net | 407-423-7149

Most people have late- onset Alzheimer’s, in which symptoms for the disease become apparent in a person’s mid- 60’s. Research suggest that there are factors beyond genetics that may play a role in development of Alzheimer’s disease. Vascular conditions such as heart disease and stroke correlate to cognitive decline. As well as metabolic conditions such as diabetes, these conditions and their relationship to Alzheimer’s is continuously being researched with clinical trials.
Participants in Alzheimer's clinical research help scientists learn how the brain changes with healthy aging and with Alzheimer’s. The clinical studies are testing ways to understand, diagnose, treat, and prevent Alzheimer's disease. Volunteering for a clinical trial is one way to help in the fight against Alzheimer's disease. Studies need participants of different ages, sexes, races, and ethnicities to ensure that results are meaningful for many people. apgresearch.net

What is the study for: Alzheimer’s/ MCI
Ages: 50-85 years old
- Must be positive for brain amyloid
- If taking Memantine or AChEl, must be on a stable dose for 12 weeks
- Must have a caregiver willing to participate until the end of the study
How long: 2.5 years
Frequency of visits: Every two weeks for the first three months, then monthly
Medication: E2609

If you qualify to participate in a study, you will receive:
- Assessments by a Board Certified Psychiatrist
- Investigational medication at no cost
- Study-related care and monitoring
- Compensation for time and travel

APG Research provides extensive service to our sponsors, physicians and research patients. Our team has a combined 40 years of clinical research experience in adult and pediatric studies including Major Depression, Autism, Anxiety, Bipolar, OCD, ADHD and Schizophrenic Disorders. apgresearch.net

Call today to see if you or someone you know would benefit from participating in one our studies.

apgresearch.net | 407-423-7149 | plus.google.com/+APGresearchNet

Are You Suffering From Major Depressive Disorder?

In the United States it is reported that upwards of 70% of patients with Major Depressive Disorder (MDD) are partial or non-responders to the first- line therapies which include SSRIs and SNRIs.

Designation FOR Adjunctive Treatment of Major Depressive Disorder (MDD), has a mechanism of action which is entire different from that of atypical antipsychotics. The drug, rapastinel, is an N-methyl-D-aspartate receptor (NMDAR) modulator with a novel and complete pharmacological mechanism of action, acting as a nonselective agent at NR2 subunits and displaying properties as a functional partial agonist in a number of pharmacological assays. apgresearch.net

At APG Clinical Research, we are conducing more research into this new drug, and invite you to refer people who meet the following criteria:
- Ages 18 and up
- With a current major depressive episode in the last 8 weeks and not exceeding 18 months in duration
- And, have no more than partial response (<50% improvement) to ongoing treatment with a protocol- allowed antidepressant

APG Research provides extensive service to our sponsors, physicians and research patients. Our team has a combined 40 years of clinical research experience in adult and pediatric studies including Major Depression, Autism, Anxiety, Bipolar, OCD, ADHD and Schizophrenic Disorders. apgresearch.net

Call today to see if your child would benefit from participating in one our studies.

apgresearch.net | 407-423-7149 | plus.google.com/+APGresearchNet

Schizophrenia in Adolescents

The psychotic disorder Schizophrenia is typically begins in late adolescence into early adulthood. The shorthand term ‘adolescent-onset’ typically refers to the onset of Schizophrenia in child and adolescent cases up to the age of 17, with the onset being exceedingly rare in cases under 10 years old.

What is Schizophrenia?
Schizophrenia is linked to structural and functional abnormalities in the regions of the brain that control coordinated thinking, perceptions, and behaviors. People who have Schizophrenia will often find it difficult to filter and process information correctly. This can often cause delusions and hallucinations that cause the afflicted persons to have a mental break from reality. Other symptoms of Schizophrenia can include disorganized thinking or speech, abnormal motor behaviors, or other negative symptoms. Negative symptoms refer to the absence of something that is typically present. This can refer to decreased emotional expression, diminished involvement in activities, or loss of speech or social interaction. While Schizophrenia usually develops over the course of several year, negative symptoms will often appear a few years before any other symptoms emerge.  

What You Can Do to Help
Volunteering for a clinical trial is one way to help in understanding and treating. Studies need participants of different ages, sexes, races, and ethnicities to ensure that results are meaningful for many people.
What is the study for: Adolescent Schizophrenia
Ages: 12-17 years old
- Must have diagnosis of Schizophrenia that is clinically stable with residual symptoms
- No medication changes within 8 weeks
How long: 10 weeks
Frequency of visits: Every 2 weeks
Medication: Sodium Benzoate
If you qualify to participate in a study, you will receive:
- Assessments by a Board Certified Psychiatrist
- Investigational medication at no cost
- Study-related care and monitoring
- Compensation for time and travel
APG Research provides extensive service to our sponsors, physicians and research patients. Our team has a combined 40 years of clinical research experience in adult and pediatric studies including Major Depression, Autism, Anxiety, Bipolar, OCD, ADHD and Schizophrenic Disorders.

Contact APG Clinical Research today to see if your child can qualify for one of our clinical studies involving Schizophrenia.

apgresearch.net | 407-423-7149 | plus.google.com/+APGresearchNet

Manic or Mixed Bipolar I Disorder

One of the most easily diagnosed forms of Bipolar disorder is Bipolar I. Noted for the presence of pronounced elevated mood, called mania, a person with Bipolar I has both episodes of mania and depression.

Symptoms of Mania
Categorized as a profound mood disturbance of elation, irritability, or expansiveness, a manic episode can drastically impair a person’s social and occupational functioning, and can also lead to hospitalization. Symptoms of a manic episode may include grandiosity, diminished need for sleep, excessive talking, or racing thoughts, among others.

Symptoms of Bipolar I Depression
Bipolar I includes the presence of depressive episodes, which can be characterized by depressed mood, or a loss of pleasure. Experiencing a depressive episode can impair one’s ability to function normally, and cause a huge amount of distress. Some symptoms of a depressive episode may include significant weight loss or gain, hypersomnia or insomnia, and loss of energy, among others.  A Bipolar I disorder episode could be diagnosed as both manic and depressive.

Volunteering for a clinical trial is one way to help in understanding and treating. Studies need participants of different ages, sexes, races, and ethnicity to ensure that results are meaningful for many people.
What is the study for: Bipolar I disorder
Ages: 10-17 years old
- Must have a primary diagnosis of Bipolar I disorder
- Must stop medications prior to starting study
How long: 8-10 months
Frequency of visits: Weekly for 15 weeks, then monthly
Medication: N/A
For cases involving patients 18 years or older we recommend the use of Equetro- FDA Approved for Adults
If you qualify to participate in a study, you will receive:
- Assessments by a Board Certified Psychiatrist
- Investigational medication at no cost
- Study-related care and monitoring
- Compensation for time and travel
APG Research provides extensive service to our sponsors, physicians and research patients. Our team has a combined 40 years of clinical research experience in adult and pediatric studies including Major Depression, Autism, Anxiety, Bipolar, OCD, ADHD and Schizophrenic Disorders.

apgresearch.net | 407-423-7149 | plus.google.com/+APGresearchNet

Autism Studies for Children

Autism Spectrum Disorder (ASD) refers to a range of conditions that can be characterized by challenges with social skills, repetitive behavior, speech, and nonverbal communication. As the term “spectrum” suggests, ASD reflects a wide variation of both strengths and challenges that differ to every person with autism. Typically Autism’s most obvious sign can start to show between the ages of two and three years of age, however diagnosis can happen as early as 18 months old.

While Autism is usually a life-long condition, those who are diagnosed with autism still benefit from interventions and therapies. It’s best to start interventions at a young age, and patients can experience the benefits of therapy throughout life. If your child has been diagnosed with Autism Spectral Disorder they may be eligible to participate in the Autism Clinical Studies with APG Clinical Research.

Volunteering for a clinical trial is one way to help in understanding and treating Autism. Studies need participants of different ages, sexes, races, and ethnicities to ensure that results are meaningful for many people.

What is the study for: Autism Spectral Disorder (ASD)

Ages: 3-8 years old
- No off label medications
- May not take ADHD medications while participating in the study

How long: 12 weeks

Frequency of visits: Every two weeks

Medication: Pancreatic Enzyme Concentrate

If you qualify to participate in a study, you will receive:
- Assessments by a Board Certified Psychiatrist
- Investigational medication at no cost
- Study-related care and monitoring
- Compensation for time and travel

APG Research provides extensive service to our sponsors, physicians and research patients. Our team has a combined 40 years of clinical research experience in adult and pediatric studies including Major Depression, Autism, Anxiety, Bipolar, OCD, ADHD and Schizophrenic Disorders.

Call today to see if your child would benefit from participating in one our studies.

apgresearch.net | 407-423-7149 | plus.google.com/+APGresearchNet